Journal article
Using symptom scores, lifestyle measures and biochemical markers to create a test for endometriosis
P Paiva, M Lappas, G Barker, M Healey
Journal of Endometriosis and Pelvic Pain Disorders | SAGE PUBLICATIONS LTD | Published : 2014
DOI: 10.5301/je.5000194
Abstract
Purpose: The purpose of this study was to develop a test to discriminate between women suffering from pelvic pain associated with presence or absence of endometriosis, using symptom visual analogue scale (VAS) scores, demographic and lifestyle factors and known and novel plasma biomarkers.Methods: This was a prospective cohort study. We recruited women presenting with pelvic pain symptoms and undergoing laparoscopy. They provided a plasma sample and completed a questionnaire assessing symptom VAS scores, lifestyle factors and demographic details. Plasma was assayed for 18 potential biomarkers. Logistic regression was used to develop a test to discriminate between women with pelvic pain assoc..
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Funding Acknowledgements
This study was funded from donations through the Women's Foundation (Royal Women's Hospital). M.L. is supported by a Career Development Fellowship from the National Health and Medical Research Council (NHMRC; grant no. 1047025). P.P. is supported by an Early Career Fellowship by the National Health and Medical Research Council (NHMRC; grant no. 1013774). Funding for the iMark Microplate absorbance reader was provided by the Medical Research Foundation for Women and Babies.